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ADInstruments ecg analysis module
Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on <t>Electrocardiogram</t> patterns. Electrocardiogram of control rats showed normal <t>ECG</t> patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.
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Fig. 4. Effect of TTM on Electrocardiogram patterns. Electrocardiogram of control rats showed normal ECG patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Article Title: Pretreatment of Tribulus terrestris L. causes anti-ischemic cardioprotection through MAPK mediated anti-apoptotic pathway in rat.

doi: 10.1016/j.biopha.2019.01.033

Figure Lengend Snippet: Fig. 4. Effect of TTM on Electrocardiogram patterns. Electrocardiogram of control rats showed normal ECG patterns, and isoproterenol treatment (85 mg/kg) showed a marked ST-segment elevation. Pretreatment of TTM (250 and 500 mg/kg) prior to isoproterenol treatment showed near normal ECG patterns. There was an increase in heart rate on isoproterenol treatment and TTM (250 and 500 mg/kg) pretreatment prior to isoproterenol treatment was able to normalize the increase in heart rate. Rats were pretreated with TTM 250 and 500 mg/kg body weight and positive control (propranolol) 15 mg/kg body weight for 21 days. Isoproterenol was injected, and after 24 h, rats were anaesthetised using ketamine (65 mg/kg body weight) and xylazine (5 mg/kg body weight) and subjected to ECG analysis.

Article Snippet: ECG recording was performed using a PowerLab data acquisition system and analysed with ECG Analysis Module (AD Instruments, Australia).

Techniques: Control, Positive Control, Injection